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(Credits for this research goes to Sathya Narayanan, Microsoft Support Engineer)
Troubleshooting long running MAPI connections to Exchange Server 2010 through Network Load Balancers : https://support.microsoft.com/kb/2535656
How to setup an Exchange 2010 CAS Array to load balance MAPI : https://blogs.technet.com/b/ucedsg/archive/2009/12/06/how-to-setup-an-exchange-2010-cas-array-to-load-balance-mapi.aspx
Microsoft Exchange 2010 CAS Array – Steps and Recommendations : https://blogs.technet.com/b/omers/archive/2010/10/11/microsoft-exchange-2010-cas-array-steps-and-recommendations.aspx
Configure Static RPC Ports on an Exchange 2010 Client Access Server : https://social.technet.microsoft.com/wiki/contents/articles/864.configure-static-rpc-ports-on-an-exchange-2010-client-access-server.aspx